Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancers

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of tumours with a typical 5 year survival rate of <40 %. DNA methylation in tumour-suppressor genes often occurs at an early stage of tumorigenesis, hence DNA methylation can be used as an early tumour biomarker. S...

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Vydáno v:BMC Cancer
Hlavní autoři: Lim, Yenkai, Wan, Yunxia, Vagenas, Dimitrios, Ovchinnikov, Dmitry A., Perry, Chris F. L., Davis, Melissa J., Punyadeera, Chamindie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034533/
https://ncbi.nlm.nih.gov/pubmed/27663357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2785-0
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