Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas

BACKGROUND: Reports of exocrine-to-endocrine reprogramming through expression or stabilization of the transcription factor neurogenin 3 (NGN3) have generated renewed interest in harnessing pancreatic plasticity for therapeutic applications. NGN3 is expressed by a population of endocrine progenitor c...

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Bibliographic Details
Published in:Cell Commun Signal
Main Authors: Shamblott, Michael J., O’Driscoll, Marci L., Gomez, Danielle L., McGuire, Dustin L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034529/
https://ncbi.nlm.nih.gov/pubmed/27659207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0146-x
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