Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate

Neurogenin 3 (NGN3) is necessary and sufficient for endocrine differentiation during pancreatic development and is expressed by a population of progenitor cells that give rise exclusively to hormone-secreting cells within islets. NGN3 protein can be detected in the adult rodent pancreas only followi...

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Publicat a:PLoS One
Autors principals: Gomez, Danielle L., O’Driscoll, Marci, Sheets, Timothy P., Hruban, Ralph H., Oberholzer, Jose, McGarrigle, James J., Shamblott, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545947/
https://ncbi.nlm.nih.gov/pubmed/26288179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133862
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