Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation

OBJECTIVE: Cardiovascular diseases (CVDs) are the leading cause of mortality in Western countries. Atherosclerosis is a multi-step inflammatory disease characterized at early stages by accumulation of cholesterol in the arterial wall followed by recruitment of immune cells. We sought to determine if...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Billon, Cyrielle, Sitaula, Sadichha, Burris, Thomas P.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034492/
https://ncbi.nlm.nih.gov/pubmed/27689012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.07.001
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