Sumoylation of IkB attenuates NF-kB-induced nitrosative stress at rostral ventrolateral medulla and cardiovascular depression in experimental brain death

BACKGROUND: Small ubiquitin-related modifier (SUMO) is a group of proteins that participates in post-translational modifications. One known SUMO target is the transcription factor nuclear factor-kB (NF-kB) that plays a pivotal role in many disease processes; sumoylation inactivates NF-kB by conjugat...

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Vydáno v:J Biomed Sci
Hlavní autoři: Tsai, Ching-Yi, Li, Faith C. H., Wu, Carol H. Y., Chang, Alice Y. W., Chan, Samuel H. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034413/
https://ncbi.nlm.nih.gov/pubmed/27658615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0283-y
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