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Phosphatidic Acid Produced by RalA-activated PLD2 Stimulates Caveolae-mediated Endocytosis and Trafficking in Endothelial Cells

Caveolae are the primary route for internalization and transendothelial transport of macromolecules, such as insulin and albumin. Caveolae-mediated endocytosis is activated by Src-dependent caveolin-1 (Cav-1) phosphorylation and subsequent recruitment of dynamin-2 and filamin A (FilA), which facilit...

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Vydáno v:J Biol Chem
Hlavní autoři: Jiang, Ying, Sverdlov, Maria S., Toth, Peter T., Huang, Long Shuang, Du, Guangwei, Liu, Yiyao, Natarajan, Viswanathan, Minshall, Richard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034062/
https://ncbi.nlm.nih.gov/pubmed/27510034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752485
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