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Genetic background limits generalizability of genotype-phenotype relationships
Genome wide association studies (GWAS) have identified numerous loci that influence risk for psychiatric diseases. Genetically engineered mice are often used to characterize genes implicated by GWAS. These studies are based on the assumption that observed genotype-phenotype relationships will genera...
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| Vydáno v: | Neuron |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033712/ https://ncbi.nlm.nih.gov/pubmed/27618673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2016.08.013 |
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