Chronic Expression of Interferon Gamma Leads to Murine Autoimmune Cholangitis with a Female Predominance

In most autoimmune diseases the serologic hallmarks of disease precede clinical pathology by years. Therefore the use of animal models in defining early disease events becomes critical. Herein we have taken advantage of a “designer” mouse with dysregulation of interferon gamma (IFNγ) characterized b...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Bae, Heekyong R., Leung, Patrick S.C., Tsuneyama, Koichi, Valencia, Julio C., Hodge, Deborah L., Kim, Seohyun, Back, Tim, Karwan, Megan, Merchant, Anand S., Baba, Nobuyuki, Feng, Dechun, Park, Ogyi, Gao, Bin, Yang, Guo-Xiang, Gershwin, M. Eric, Young, Howard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033675/
https://ncbi.nlm.nih.gov/pubmed/27178326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28641
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