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In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation
Tissue oxygenation is a driving parameter of the tumor microenvironment and hypoxia can be a prognostic indicator of aggressiveness, metastasis, and poor response to therapy. Here we report a chemiluminescence imaging (CLI) agent based on the oxygen-dependent reduction of a nitroaromatic spiroadaman...
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| Publicado no: | Anal Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033617/ https://ncbi.nlm.nih.gov/pubmed/27054463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b01096 |
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