In Silico Oncology: Quantification of the In Vivo Antitumor Efficacy of Cisplatin-Based Doublet Therapy in Non-Small Cell Lung Cancer (NSCLC) through a Multiscale Mechanistic Model

The 5-year survival of non-small cell lung cancer patients can be as low as 1% in advanced stages. For patients with resectable disease, the successful choice of preoperative chemotherapy is critical to eliminate micrometastasis and improve operability. In silico experimentations can suggest the opt...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kolokotroni, Eleni, Dionysiou, Dimitra, Veith, Christian, Kim, Yoo-Jin, Sabczynski, Jörg, Franz, Astrid, Grgic, Aleksandar, Palm, Jan, Bohle, Rainer M., Stamatakos, Georgios
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033576/
https://ncbi.nlm.nih.gov/pubmed/27657742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005093
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