Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?

BACKGROUND: 5-FU based chemotherapy is the most common first line regimen used for metastatic colorectal cancer (mCRC). Identification of predictive markers of response to chemotherapy is a challenging approach for drug selection. The present study analyzes the predictive role of 5-FU degradation ra...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Botticelli, Andrea, Borro, Marina, Onesti, Concetta Elisa, Strigari, Lidia, Gentile, Giovanna, Cerbelli, Bruna, Romiti, Adriana, Occhipinti, Mario, Sebastiani, Claudia, Lionetto, Luana, Marchetti, Luca, Simmaco, Maurizio, Marchetti, Paolo, Mazzuca, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033390/
https://ncbi.nlm.nih.gov/pubmed/27656891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163105
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