Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice

Transmembrane adaptor proteins (TRAPs) are important organisers for the transduction of immunoreceptor-mediated signals. Prr7 is a TRAP that regulates T cell receptor (TCR) signalling and potently induces cell death when overexpressed in human Jurkat T cells. Whether endogenous Prr7 has a similar fu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hrdinka, Matous, Sudan, Kritika, Just, Sissy, Drobek, Ales, Stepanek, Ondrej, Schlüter, Dirk, Reinhold, Dirk, Jordan, Bryen A., Gintschel, Patricia, Schraven, Burkhart, Kreutz, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033326/
https://ncbi.nlm.nih.gov/pubmed/27657535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162863
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