An integrative analysis of the InR/PI3K/Akt network identifies the dynamic response to Insulin signaling

Insulin regulates an essential conserved signaling pathway affecting growth, proliferation and metabolism. To expand our understanding of the insulin pathway, we combine biochemical, genetic and computational approaches to build a comprehensive Drosophila InR/PI3K/Akt network. First, we map the dyna...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Vinayagam, Arunachalam, Kulkarni, Meghana M., Sopko, Richelle, Sun, Xiaoyun, Hu, Yanhui, Nand, Ankita, Villalta, Christians, Moghimi, Ahmadali, Yang, Xuemei, Mohr, Stephanie E., Hong, Pengyu, Asara, John, Perrimon, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033061/
https://ncbi.nlm.nih.gov/pubmed/27626673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.029
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