Modeling the Chronic Loss of Optic Nerve Axons and the Effects on the Retinal Nerve Fiber Layer Structure in Primary Disorder of Myelin

PURPOSE: We determined whether the chronic lack of optic nerve myelination and subsequent axon loss is associated with optical coherence tomography (OCT) changes in the retinal nerve fiber layer (RNFL), and whether this models what occurs in multiple sclerosis (MS) and confers its use as a surrogate...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Teixeira, Leandro B. C., Ver Hoeve, James N., Mayer, Joshua A., Dubielzig, Richard R., Smith, Chelsey M., Radcliff, Abigail B., Duncan, Ian D.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2016
Fag:
Retina
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032912/
https://ncbi.nlm.nih.gov/pubmed/27654412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19871
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