Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes

Aging and exposure to stress would determine the chondrocyte phenotype in osteoarthritis (OA). In particular, chronic inflammation may contribute to stress-induced senescence of chondrocytes and cartilage degeneration during OA progression. Recent studies have shown that adipose-derived mesenchymal...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Platas, Julia, Guillén, Maria Isabel, del Caz, Maria Dolores Pérez, Gomar, Francisco, Castejón, Miguel Angel, Mirabet, Vicente, Alcaraz, Maria José
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5032691/
https://ncbi.nlm.nih.gov/pubmed/27490266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101007
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