Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling

Intervertebral disc (IVD) degeneration is characterized by significant biochemical and histomorphological alterations, such as loss of extracellular matrix (ECM) integrity, by abnormal synthesis of ECM main components, resultant from altered anabolic/catabolic cell activities and cell death. Mesench...

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Udgivet i:Sci Rep
Main Authors: Pereira, Catarina Leite, Teixeira, Graciosa Q., Ribeiro-Machado, Cláudia, Caldeira, Joana, Costa, Madalena, Figueiredo, Francisco, Fernandes, Rui, Aguiar, Paulo, Grad, Sibylle, Barbosa, Mário A., Gonçalves, Raquel M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031983/
https://ncbi.nlm.nih.gov/pubmed/27652931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33836
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