Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling

Intervertebral disc (IVD) degeneration is characterized by significant biochemical and histomorphological alterations, such as loss of extracellular matrix (ECM) integrity, by abnormal synthesis of ECM main components, resultant from altered anabolic/catabolic cell activities and cell death. Mesench...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Pereira, Catarina Leite, Teixeira, Graciosa Q., Ribeiro-Machado, Cláudia, Caldeira, Joana, Costa, Madalena, Figueiredo, Francisco, Fernandes, Rui, Aguiar, Paulo, Grad, Sibylle, Barbosa, Mário A., Gonçalves, Raquel M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031983/
https://ncbi.nlm.nih.gov/pubmed/27652931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33836
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