Dopaminergic Receptors on CD4+ T Naive and Memory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson’s Disease

Parkinson’s disease (PD) is characterized by loss of dopaminergic neurons in substantia nigra pars compacta, α-synuclein (α-syn)-rich intraneuronal inclusions (Lewy bodies), and microglial activation. Emerging evidence suggests that CD4+ T lymphocytes contribute to neuroinflammation in PD. Since the...

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Pubblicato in:Sci Rep
Autori principali: Kustrimovic, Natasa, Rasini, Emanuela, Legnaro, Massimiliano, Bombelli, Raffaella, Aleksic, Iva, Blandini, Fabio, Comi, Cristoforo, Mauri, Marco, Minafra, Brigida, Riboldazzi, Giulio, Sanchez-Guajardo, Vanesa, Marino, Franca, Cosentino, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031979/
https://ncbi.nlm.nih.gov/pubmed/27652978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33738
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