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Dysferlin-mediated phosphatidylserine sorting engages macrophages in sarcolemma repair

Failure to repair the sarcolemma leads to muscle cell death, depletion of stem cells and myopathy. Hence, membrane lesions are instantly sealed by a repair patch consisting of lipids and proteins. It has remained elusive how this patch is removed to restore cell membrane integrity. Here we examine s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Middel, Volker, Zhou, Lu, Takamiya, Masanari, Beil, Tanja, Shahid, Maryam, Roostalu, Urmas, Grabher, Clemens, Rastegar, Sepand, Reischl, Markus, Nienhaus, Gerd Ulrich, Strähle, Uwe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031802/
https://ncbi.nlm.nih.gov/pubmed/27641898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12875
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