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Indomethacin Treatment of Mice with Premalignant Oral Lesions Sustains Cytokine Production and Slows Progression to Cancer

Current treatment options for head and neck squamous cell carcinoma (HNSCC) patients are often ineffective due to tumor-localized and systemic immunosuppression. Using the 4-NQO mouse model of oral carcinogenesis, this study showed that premalignant oral lesion cells produce higher levels of the imm...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Johnson, Sara D., Young, M. Rita I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031768/
https://ncbi.nlm.nih.gov/pubmed/27713748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00379
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