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Indomethacin Treatment of Mice with Premalignant Oral Lesions Sustains Cytokine Production and Slows Progression to Cancer

Current treatment options for head and neck squamous cell carcinoma (HNSCC) patients are often ineffective due to tumor-localized and systemic immunosuppression. Using the 4-NQO mouse model of oral carcinogenesis, this study showed that premalignant oral lesion cells produce higher levels of the imm...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Johnson, Sara D., Young, M. Rita I.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031768/
https://ncbi.nlm.nih.gov/pubmed/27713748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00379
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