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Recent advances in T-cell engineering for use in immunotherapy

Adoptive T-cell therapies have shown exceptional promise in the treatment of cancer, especially B-cell malignancies. Two distinct strategies have been used to redirect the activity of ex vivo engineered T cells. In one case, the well-known ability of the T-cell receptor (TCR) to recognize a specific...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Sharma, Preeti, Kranz, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031132/
https://ncbi.nlm.nih.gov/pubmed/27703664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9073.1
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