Epstein-Barr viral miRNAs inhibit antiviral CD4(+) T cell responses targeting IL-12 and peptide processing

Epstein-Barr virus (EBV) is a tumor virus that establishes lifelong infection in most of humanity, despite eliciting strong and stable virus-specific immune responses. EBV encodes at least 44 miRNAs, most of them with unknown function. Here, we show that multiple EBV miRNAs modulate immune recogniti...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Tagawa, Takanobu, Albanese, Manuel, Bouvet, Mickaël, Moosmann, Andreas, Mautner, Josef, Heissmeyer, Vigo, Zielinski, Christina, Lutter, Dominik, Hoser, Jonathan, Hastreiter, Maximilian, Hayes, Mitch, Sugden, Bill, Hammerschmidt, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030804/
https://ncbi.nlm.nih.gov/pubmed/27621419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160248
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