Epstein-Barr viral miRNAs inhibit antiviral CD4(+) T cell responses targeting IL-12 and peptide processing

Epstein-Barr virus (EBV) is a tumor virus that establishes lifelong infection in most of humanity, despite eliciting strong and stable virus-specific immune responses. EBV encodes at least 44 miRNAs, most of them with unknown function. Here, we show that multiple EBV miRNAs modulate immune recogniti...

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Vydáno v:J Exp Med
Hlavní autoři: Tagawa, Takanobu, Albanese, Manuel, Bouvet, Mickaël, Moosmann, Andreas, Mautner, Josef, Heissmeyer, Vigo, Zielinski, Christina, Lutter, Dominik, Hoser, Jonathan, Hastreiter, Maximilian, Hayes, Mitch, Sugden, Bill, Hammerschmidt, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030804/
https://ncbi.nlm.nih.gov/pubmed/27621419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160248
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