The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

Pentraxin 3 (PTX3) is a fluid-phase pattern recognition receptor of the humoral innate immune system with ancestral antibody-like properties but unknown antibody-inducing function. In this study, we found binding of PTX3 to splenic marginal zone (MZ) B cells, an innate-like subset of antibody-produc...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Chorny, Alejo, Casas-Recasens, Sandra, Sintes, Jordi, Shan, Meimei, Polentarutti, Nadia, García-Escudero, Ramón, Walland, A. Cooper, Yeiser, John R., Cassis, Linda, Carrillo, Jorge, Puga, Irene, Cunha, Cristina, Bastos, Hélder, Rodrigues, Fernando, Lacerda, João F., Morais, António, Dieguez-Gonzalez, Rebeca, Heeger, Peter S., Salvatori, Giovanni, Carvalho, Agostinho, Garcia-Sastre, Adolfo, Blander, J. Magarian, Mantovani, Alberto, Garlanda, Cecilia, Cerutti, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030794/
https://ncbi.nlm.nih.gov/pubmed/27621420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150282
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