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Probing lipid- and drug-binding domains with fluorescent dyes

A series of 2- and 3-OH Nile red dyes was prepared in order to generate water-soluble probes that could be used to probe lipid binding to proteins. Various substitutions in positions 2-/3-, 6-, and 7-shifted wavelengths while maintaining the environmental sensitivity of Nile red. In order to increas...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Black, Shannon L., Stanley, Will A., Filipp, Fabian V., Bhairo, Michelle, Verma, Ashwani, Wichmann, Oliver, Sattler, Michael, Wilmanns, Matthias, Schultz, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030716/
https://ncbi.nlm.nih.gov/pubmed/18024138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.10.080
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