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DDX6 transfers P-TEFb kinase to the AF4/AF4N (AFF1) super elongation complex

AF4/AFF1 and AF5/AFF4 are both backbones for the assembly of “super elongation complexes” (SECs) that exert 2 distinct functions after the recruitment of P-TEFb from the 7SK snRNP: (1) initiation and elongation of RNA polymerase II gene transcription, and (2) modification of transcribed gene regions...

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Publicado en:Am J Blood Res
Autores principales: Mück, Fabian, Bracharz, Silvia, Marschalek, Rolf
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030405/
https://ncbi.nlm.nih.gov/pubmed/27679741
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