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Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism.

We have previously shown that lipoprotein(a) [Lp(a)], an atherogenic lipoprotein that contains apolipoprotein(a), which shares partial structural homology to plasminogen, binds to a plasmin-modified fibrin surface, and we have postulated that this interaction may be atherogenic. Moderate elevations...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Harpel, P C, Chang, V T, Borth, W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.21.10193
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