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Opioid Induced Loss of Local Anesthetic Potency in the Rat Sciatic Nerve

BACKGROUND: Previous evidence suggests that opioid tolerant patients are less responsive to local anesthetics (LAs) for postoperative pain management. METHODS: To determine whether this apparent loss of LA potency is due to an intrinsic change in the peripheral nerve, the effect of systemic morphine...

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Vydáno v:Anesthesiology
Hlavní autoři: Liu, Qing, Gold, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030162/
https://ncbi.nlm.nih.gov/pubmed/27428823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001239
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