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Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis

The importance of mechanical activity in the regulation of muscle progenitors during chick development has not been investigated. We show that immobilization decreases NOTCH activity and mimics a NOTCH loss-of-function phenotype, a reduction in the number of muscle progenitors and increased differen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Esteves de Lima, Joana, Bonnin, Marie-Ange, Birchmeier, Carmen, Duprez, Delphine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030091/
https://ncbi.nlm.nih.gov/pubmed/27554485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.15593
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