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Preparation of Two Types of Polymeric Micelles Based on Poly(β-L-Malic Acid) for Antitumor Drug Delivery

Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. In this work, two types of CPT-conjugated polymers were synthesized based on poly(β-L-malic acid) (PMLA) derivatives. Folic acid (FA) was introduced into the polymers as tumor targeting group. The mi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yang, Tiehong, Li, Wei, Duan, Xiao, Zhu, Lin, Fan, Li, Qiao, Youbei, Wu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029928/
https://ncbi.nlm.nih.gov/pubmed/27649562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162607
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