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Assessment of Carbon Dioxide, Carbon Dioxide/Oxygen, Isoflurane and Pentobarbital Killing Methods in Adult Female Sprague-Dawley Rats

BACKGROUND: Exposure to carbon dioxide (CO(2)) gas as a killing method is aversive and exposure to high concentrations is likely to be painful. Bradycardia during exposure to CO(2) is associated with nociception and pain. However, it is unclear if bradycardia occurs before loss of consciousness as d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chisholm, Jessica M., Pang, Daniel S. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029904/
https://ncbi.nlm.nih.gov/pubmed/27648836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162639
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