HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1

Based on previous findings supporting HLA-F as a ligand for KIR3DL2 and KIR2DS4, we investigated the potential for MHC-I open conformers (OCs) as ligands for KIR3DS1 and KIR3DL1 through interactions measured by surface plasmon resonance. These measurements showed physical binding of KIR3DS1 but not...

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Udgivet i:PLoS One
Main Authors: Burian, Aura, Wang, Kevin L., Finton, Kathryn A. K., Lee, Ni, Ishitani, Akiko, Strong, Roland K., Geraghty, Daniel E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029895/
https://ncbi.nlm.nih.gov/pubmed/27649529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163297
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