Upper Limb Evaluation in Duchenne Muscular Dystrophy: Fat-Water Quantification by MRI, Muscle Force and Function Define Endpoints for Clinical Trials

OBJECTIVE: A number of promising experimental therapies for Duchenne muscular dystrophy (DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation-dependent functional tests to assess outcome. Quantitative muscle magnetic resonance imaging (MRI) could offer a valuable alte...

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Publicat a:PLoS One
Autors principals: Ricotti, Valeria, Evans, Matthew R. B., Sinclair, Christopher D. J., Butler, Jordan W., Ridout, Deborah A., Hogrel, Jean-Yves, Emira, Ahmed, Morrow, Jasper M., Reilly, Mary M., Hanna, Michael G., Janiczek, Robert L., Matthews, Paul M., Yousry, Tarek A., Muntoni, Francesco, Thornton, John S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029878/
https://ncbi.nlm.nih.gov/pubmed/27649492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162542
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