Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy

Several clinical trials indicate that concurrent administration of tyrosine kinase inhibitors (TKIs, such as gefitinib or erlotinib) with chemotherapy agents fails to improve overall survival in advanced non-small cell lung cancer (NSCLC) patients. However, the precise mechanisms underlying the anta...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Xiao-Qiu, Liu, Jia-Tao, Fan, Lu-Lu, Liu, Yu, Cheng, Liang, Wang, Fang, Yu, Han-Qing, Gao, Jian, Wei, Wei, Wang, Hua, Sun, Guo-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029725/
https://ncbi.nlm.nih.gov/pubmed/27029054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8358
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