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MicroRNA-1229 overexpression promotes cell proliferation and tumorigenicity and activates Wnt/β-catenin signaling in breast cancer

Constitutive activation of the Wnt/β-catenin pathway promotes malignant proliferation and it is inversely correlated with the prognosis of patients with breast cancer. However, mutations in key regulators, such as APC, Axin and β-catenin, contribute to aberrant activation of the Wnt/β-catenin signal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Tan, Zhanyao, Zheng, Haiqing, Liu, Xiangxia, Zhang, Wenhui, Zhu, Jinrong, Wu, Geyan, Cao, Lixue, Song, Junwei, Wu, Shu, Song, Libing, Li, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029685/
https://ncbi.nlm.nih.gov/pubmed/26992223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8119
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