MicroRNA-16 sensitizes breast cancer cells to paclitaxel through suppression of IKBKB expression

Paclitaxel (Taxol) is an effective chemotherapeutic agent for treating breast cancer patients. However, chemoresistance is a major obstacle in cancer treatment. Here, we showed that overexpression of miR-16 promoted Taxol-induced cytotoxicity and apoptosis in breast cancer cells. Furthermore, IκB ki...

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Опубликовано в: :Oncotarget
Главные авторы: Tang, Xueyuan, Jin, Long, Cao, Peiguo, Cao, Ke, Huang, Chenghui, Luo, Yanwei, Ma, Jian, Shen, Shourong, Tan, Ming, Li, Xiayu, Zhou, Ming
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029655/
https://ncbi.nlm.nih.gov/pubmed/26993770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8056
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