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β-casein nanovehicles for oral delivery of chemotherapeutic drug combinations overcoming P-glycoprotein-mediated multidrug resistance in human gastric cancer cells

Multidrug resistance (MDR) is a primary obstacle to curative cancer therapy. We have previously demonstrated that β-casein (β-CN) micelles (β-CM) can serve as nanovehicles for oral delivery and target-activated release of hydrophobic drugs in the stomach. Herein we introduce a novel nanosystem based...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bar-Zeev, Maya, Assaraf, Yehuda G., Livney, Yoav D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029629/
https://ncbi.nlm.nih.gov/pubmed/26989076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8019
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