The emerging role of FTY720 (Fingolimod) in cancer treatment

FTY720 (Fingolimod) is a clinically approved immunomodulating therapy for multiple sclerosis that sequesters T-cells to lymph nodes through functional antagonism of sphingosine-1-phosphate 1 receptor. FTY720 also demonstrates a proven efficacy in multiple in vitro and in vivo cancer models, suggesti...

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Bibliographic Details
Published in:Oncotarget
Main Authors: White, Christopher, Alshaker, Heba, Cooper, Colin, Winkler, Matthias, Pchejetski, Dmitri
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029614/
https://ncbi.nlm.nih.gov/pubmed/27036015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7145
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