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Modulation of Superficial Zone Protein/Lubricin/PRG4 by Kartogenin and Transforming Growth Factor-β1 in Surface Zone Chondrocytes in Bovine Articular Cartilage

OBJECTIVE: Superficial zone protein (SZP)/lubricin/PRG4 functions as a boundary lubricant in articular cartilage to decrease friction and wear. As articular cartilage lubrication is critical for normal joint function, the accumulation of SZP at the surface of cartilage is important for joint homeost...

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Publicat a:Cartilage
Autors principals: Miyatake, Kazumasa, Iwasa, Kenjiro, McNary, Sean M., Peng, Gordon, Reddi, A. Hari
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029568/
https://ncbi.nlm.nih.gov/pubmed/27688846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603516630789
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