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CCR4 and CAF1 deadenylases have an intrinsic activity to remove the post-poly(A) sequence
MicroRNAs (miRNAs) recruit the CCR4–NOT complex, which contains two deadenylases, CCR4 and CAF1, to promote shortening of the poly(A) tail. Although both CCR4 and CAF1 generally have a strong preference for poly(A) RNA substrates, it has been reported from yeast to humans that they can also remove n...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5029453/ https://ncbi.nlm.nih.gov/pubmed/27484313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057679.116 |
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