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CXCR2 Signaling Protects Oligodendrocyte Progenitor Cells from IFN-γ/CXCL10-Mediated Apoptosis

Infiltration of activated lymphocytes into the central nervous system (CNS) is potentially harmful by damaging resident cells through release of cytokines. Among these is IFN-γ that is secreted by activated natural killer (NK) cells and T lymphocytes and can exert a cytotoxic effect on resident glia...

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Publicado en:Glia
Main Authors: TIROTTA, EMANUELE, RANSOHOFF, RICHARD M., LANE, THOMAS E.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029281/
https://ncbi.nlm.nih.gov/pubmed/21656856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21195
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