Synthesis and chemical reactivity of a 6-Me-3,2-hydroxypyridinone dithiazolide with primary amines: a route to new hexadentate chelators for hard metal(III) ions

A hydroxypyridinone building block, bifunctionalized with thiazoline, has been prepared from orthogonally protected 2-(3-(benzyloxy)-4-(ethoxycarbonyl)-6-methyl-2-oxopyridin-1(2H)-yl) acetic acid. The reactivity of the dithiazolide has been explored with two primary amines, leading to the synthesis...

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Veröffentlicht in:J Heterocycl Chem
Hauptverfasser: Pailloux, Sylvie L., Nguyen, Sean, Zhou, Stephanie, Hom, Marisa E., Keyser, Michelle N., Smiles, Danil, Raymond, Kenneth N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029124/
https://ncbi.nlm.nih.gov/pubmed/27667855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jhet.2372
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