Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells

BACKGROUND: Chemo-resistance is still a major obstacle in efforts to overcome acute myeloid leukemia (AML). An emerging concept has proposed that interactions between the bone marrow (BM) microenvironment and leukemia cells reduce the sensitivity of the leukemia cells to chemotherapy. As an importan...

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Bibliografiske detaljer
Udgivet i:J Exp Clin Cancer Res
Main Authors: Zhai, Yuanmei, Zhang, Jing, Wang, Hui, Lu, Wei, Liu, Sihong, Yu, Yehua, Weng, Wei, Ding, Zhiyong, Zhu, Qi, Shi, Jun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029001/
https://ncbi.nlm.nih.gov/pubmed/27643489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0405-0
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