Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells

BACKGROUND: Chemo-resistance is still a major obstacle in efforts to overcome acute myeloid leukemia (AML). An emerging concept has proposed that interactions between the bone marrow (BM) microenvironment and leukemia cells reduce the sensitivity of the leukemia cells to chemotherapy. As an importan...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhai, Yuanmei, Zhang, Jing, Wang, Hui, Lu, Wei, Liu, Sihong, Yu, Yehua, Weng, Wei, Ding, Zhiyong, Zhu, Qi, Shi, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029001/
https://ncbi.nlm.nih.gov/pubmed/27643489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0405-0
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