SEPT9 and SHOX2 DNA methylation status and its utility in the diagnosis of colonic adenomas and colorectal adenocarcinomas

BACKGROUND: Colorectal cancer (CRC) appear to arise from precursor lesions in a well-characterized adenoma-carcinoma sequence. Significant efforts have been invested to develop biomarkers that identify early adenocarcinomas and adenomas with high-grade dysplasia, since these are believed to harbor a...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Semaan, Alexander, van Ellen, Anne, Meller, Sebastian, Bergheim, Dominik, Branchi, Vittorio, Lingohr, Philipp, Goltz, Diane, Kalff, Jörg C., Kristiansen, Glen, Matthaei, Hanno, Pantelis, Dimitrios, Dietrich, Dimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028994/
https://ncbi.nlm.nih.gov/pubmed/27660666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0267-5
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