Chemotherapy plus Ofatumumab at Standard or Mega dose in relapsed CLL (COSMIC) trial: study protocol for a phase II randomised controlled trial

BACKGROUND: Chronic lymphocytic leukaemia (CLL) is the most common adult leukaemia. Combination immunochemotherapy such as fludarabine, cyclophosphamide and rituximab is the standard first line therapy in fit patients, but there is limited evidence regarding the optimal treatment of patients after r...

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Enregistré dans:
Détails bibliographiques
Publié dans:Trials
Auteurs principaux: Howard, Dena R., Munir, Talha, Hockaday, Anna, Rawstron, Andy C., Collett, Laura, Oughton, Jamie B., Allsup, David, Bloor, Adrian, Phillips, David, Hillmen, Peter
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Study Protocol
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028943/
https://ncbi.nlm.nih.gov/pubmed/27645620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1581-0
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