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Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol

BACKGROUND: Previous reports have suggested that advanced glycation end products (AGEs) participate in the pathogenesis of diabetic macroangiopathy. Our previous study have found that AGEs can increase the lipid droplets accumulation in aortas of diabetic rats, but the current understanding of the m...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Xu, Lei, Wang, Yi-Ru, Li, Pei-Cheng, Feng, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028926/
https://ncbi.nlm.nih.gov/pubmed/27644038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0334-0
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