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Genetic Characterization of Plasmodium Putative Pantothenate Kinase Genes Reveals Their Essential Role in Malaria Parasite Transmission to the Mosquito

The metabolic machinery for the biosynthesis of Coenzyme A (CoA) from exogenous pantothenic acid (Vitamin B(5)) has long been considered as an excellent target for the development of selective antimicrobials. Earlier studies in the human malaria parasite Plasmodium falciparum have shown that pantoth...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hart, Robert J., Cornillot, Emmanuel, Abraham, Amanah, Molina, Emily, Nation, Catherine S., Ben Mamoun, Choukri, Aly, Ahmed S. I.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028760/
https://ncbi.nlm.nih.gov/pubmed/27644319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33518
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