Genome-Wide Anaplasma phagocytophilum AnkA-DNA Interactions Are Enriched in Intergenic Regions and Gene Promoters and Correlate with Infection-Induced Differential Gene Expression

Anaplasma phagocytophilum, an obligate intracellular prokaryote, infects neutrophils, and alters cardinal functions via reprogrammed transcription. Large contiguous regions of neutrophil chromosomes are differentially expressed during infection. Secreted A. phagocytophilum effector AnkA transits int...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Dumler, J. Stephen, Sinclair, Sara H., Pappas-Brown, Valeria, Shetty, Amol C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028410/
https://ncbi.nlm.nih.gov/pubmed/27703927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2016.00097
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