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Synthesis of polybrominated benzimidazole and benzotriazole derivatives containing a tetrazole ring and their cytotoxic activity

ABSTRACT: A series of new benzimidazole and benzotriazole derivatives containing a tetrazole moiety was synthesized by N-alkylation of 5-aryltetrazole with 4,5,6,7-tetrabromo-1-(3-chloropropyl)-1H-benzimidazole and 4,5,6,7-tetrabromo-2-(3-chloropropyl)-2H-benzotriazole. The reaction was regioselecti...

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Detalhes bibliográficos
Publicado no:Monatsh Chem
Main Authors: Łukowska-Chojnacka, Edyta, Wińska, Patrycja, Wielechowska, Monika, Bretner, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Vienna 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028404/
https://ncbi.nlm.nih.gov/pubmed/27729714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00706-016-1785-8
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