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TP53 Mutation, Mitochondria and Cancer
Under normal conditions, basal levels of wild-type p53 promote mitochondrial function through multiple mechanisms. Remarkably, some missense mutations of p53, in contrast to the null state, can result in the retention of its metabolic activities. These effects are particularly prominent in the mitoc...
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| Publicado no: | Curr Opin Genet Dev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028230/ https://ncbi.nlm.nih.gov/pubmed/27003724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2016.02.007 |
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