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Role of LTA4H Polymorphism in Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Occurrence and Clinical Severity in Patients Infected with HIV

BACKGROUND: Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory phenomenon complicating HIV management in coincidental tuberculosis (TB) infection, upon immune reconstitution driven by antiretroviral therapy (ART). Leukotriene A4 hydroxylase (...

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Veröffentlicht in:PLoS One
Hauptverfasser: Narendran, Gopalan, Kavitha, Dhanasekaran, Karunaianantham, Ramesh, Gil-Santana, Leonardo, Almeida-Junior, Jilson L., Reddy, Sirasanambatti Devarajulu, Kumar, Marimuthu Makesh, Hemalatha, Haribabu, Jayanthi, Nagesh Nalini, Ravichandran, Narayanan, Krishnaraja, Raja, Prabhakar, Angamuthu, Manoharan, Tamizhselvan, Nithyananthan, Lokeswaran, Arjunan, Gunasundari, Natrajan, Mohan, Swaminathan, Soumya, Andrade, Bruno B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028072/
https://ncbi.nlm.nih.gov/pubmed/27643598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163298
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